岳学田，博士，教授，博士研究生导师
教育经历：
2009.9-2012.6 山东大学，免疫学博士
2006.9-2009.4 浙江理工大学，生化与分子生物学硕士
2001.9-2005.7 聊城大学，生物工程学士
工作经历：
2021.1-至今 山东大学，基础医学院，教授
2018.3-至今 山东大学，基础医学院，研究员
2013.1-2018.1 美国罗格斯大学，新泽西肿瘤研究中心，博士后
研究方向：
细胞压力应激与肝脏疾病
科研项目：
1. 82470609 PRMT5介导Parkin精氨酸甲基化调控线粒体自噬在NASH中的作用和机制研究 国家自然科学基金委 202501-202812 49万 主持
代表性成果：
1. Sun M, Zhao M, Li R, Zhang Y, Shi X, Ding C, Ma C, Lu J*, Yue X*. SHMT2 promotes papillary thyroid cancer metastasis through epigenetic activation of AKT signaling, Cell Death Dis. 2024 Jan 25;15(1):87. （最后通讯）
2. Zhang Y, Fan Y, Hu H, Zhang X, Wang Z, Wu Z, Wang L, Yu X, Song X, Xiang P, Zhang X, Wang T, Tan S, Li C, Gao L, Liang X, Li S, Li N, Yue X*, Ma C*. ZHX2 emerges as a negative regulator of mitochondrial oxidative phosphorylation during acute liver injury，Nat Commun. 2023 Nov 18;14(1):7527. （共同通讯）
3. Kong Y, Wu M, Wan X, Sun M, Zhang Y, Wu Z, Li C, Liang X, Gao L, Ma C, Yue X*. Lipophagy-mediated cholesterol synthesis inhibition is required for the survival of hepatocellular carcinoma under glutamine deprivation，Redox Biol. 2023 Jul;63:102732. （最后通讯）
4. Yue X, Zhang C, Zhao Y, Liu J, Lin AW, Tan VM, Drake JM, Liu L, Boateng MN, Li J, Feng Z*, Hu W*. Gain-of-function mutant p53 activates small GTPase Rac1 through SUMOylation to promote tumor progression. Genes Dev. 2017;31(16):1641-1654.
5. Yue X, Zhao Y, Xu Y, Zheng M, Feng Z*, Hu W*. Mutant p53 in cancer: Accumulation, gain-of-function and therapy. J Mol Biol. 2017. 2836(17)30163-8.
6. Yue X, Zhao Y, Huang G, Li J, Zhu J, Feng Z, Hu W*. A novel mutant p53 binding partner BAG5 stabilizes mutant p53 and promotes mutant p53 GOFs in tumorigenesis. Cell Discov. 2016;2:16039. eCollection 2016.
7. Yue X, Zhao Y, Liu J, Zhang C, Yu H, Wang J, Zheng T, Liu L, Li J, Feng Z*, Hu W*. BAG2 promotes tumorigenesis through enhancing mutant p53 protein levels and function. Elife. 2015. 4: e08401.
8. Yue X, Zhang Z, Liang X, Gao L, Zhang X, Zhao D, Liu X, Ma H, Guo M, Spear BT, Gong Y, Ma C*. Zinc fingers and homeoboxes 2 inhibits hepatocellular carcinoma cell proliferation and represses expression of Cyclins A and E. Gastroenterology. 2012. 142: 1559-1570.
联系方式：E-mail：yuexu@sdu.edu.cn
