梁春惠，博士，助理研究员          
学习经历：

2011.9-2015.7 济南大学山东省医学科学院医学与生命科学学院，制药工程专业学士

2015.9-2020.7 南开大学生命科学学院，生物化学与分子生物学博士

研究工作经历：

2020.8-至今 山东大学助理研究员

教学工作：

承担本科生«细胞生物学»等课程的教学与实验工作。

研究方向：

多肽小分子水凝胶在抗癌药物递送方面的应用，肿瘤中铁死亡的分子机制研究以及多肽小分子在肿瘤铁死亡过程当中的应用。

代表性论文：

1. Liang, C. H.; Zheng, D. B.; Shi, F.; Xu, T. Y.; Yang, C. H.; Liu, J. F.; Wang, L.*; Yang, Z. M.*, Enzyme-assisted peptide folding, assembly and anti-cancer properties. Nanoscale, 2017, 9, 11987-11993.

2. Liang, C. H.; Zhang, L. S.; Zhao, W. N.; Xu, L. L.; Chen, Y. X.; Wang, F. Q.*; Wang, L.*; Yang, Z. M.*; Supramolecular Nanofibers of Drug-Peptide Amphiphile and Affibody Suppress HER2+ Tumor Growth. Advanced Healthcare Materials, 2018, 7.

3. Liang, C. H.; Yan, X. R.; Zhang, R. S.; Xu, T. Y.; Zheng, D. B.; Tan, Z. Q.; Chen, Y. X.; Gao, Z. F.; Wang, L.; Li, X. Y.*; Yang, Z. M.*, Enhanced cellular uptake and nuclear accumulation of drug-peptide nanomedicines prepared by enzyme-instructed self-assembly. Journal of controlled release, 2019, 317, 109-117.

4. Liang, C. H.^#; Wang, Z. Y.^#; Xu, T. Y.; Chen, Y. X.; Zheng, D. B.; Zhang, L. S.; Zhang, W. W.; Yang, Z. M.; Shi, Y.*; Gao, J.*, Preorganization increases the self-assembling ability and anti-tumor efficacy of peptide-nanomedicine. ACS Applied Materials & Interfaces, 2020. 12, 20, 22492-22498.

5. Wang, Z. Y.^#; Liang, C. H.^#; Shang Y. N.; He, S. S.; Wang, L.; Yang, Z. M.*, Narrowing the diversification of supramolecular assemblies by preorganization. Chemical Communications, 2018, 54, 2751-2754.

6. Liang, C. H.; Chen, Y. X.; Zheng, D. B.; Xu, T. Y.; Pu, G. J.; Chen, Y. M.; Wang, L.; Yang, Z. M.*; Wang, H. M.*, Pathway-Dependent Supramolecular Polymerization of Camptothecin Derivatives into Filaments for Chemotherapy and Imaging . Applied Materials Today.

7. Xu, T. Y.; Liang, C. H.; Ji, S. L.; Ding, D.; Kong, D. L.; Wang, L.*; Yang, Z. M.*, Surface-Induced Hydrogelation for Fluorescence and Naked-Eye Detections of Enzyme Activity in Blood, Analytical Chemistry. 2016, 88, 14: 7318-7323.

8. Wang, Z. Y.; Liang, C. H.; Shi, F.; He, T.; Gong, C. Y.; Wang, L.; Yang, Z. M.*, Cancer vaccines using supramolecular hydrogels of NSAID-modified peptides as adjuvants abolish tumorigenesis. Nanoscale, 2017, 9, 14058-14064.

9. Xu, T. Y.; Liang, C. H.; Zheng, D. B.; Yan, X. R.; Chen, Y. X.; Chen. Y. M.; Li, X. X.; Shi, Y.; Wang, L.; Yang, Z. M.*, Nuclear delivery of dual anticancer drug-based nanomedicine constructed by cisplatinum-induced peptide self-assembly. Nanoscale. 2020, 12, 28:15275-15282.

联系方式

济南市文化西路44号教学六楼, 6604室
Email: liangch@sdu.edu.cn